On event viewer you might see Event ID 531 – ESE – Data corruption:

Exchange 2010 event id 531 - database corruption
Exchange 2010 Event ID 531 - Database Corruption 1

Solution:

Open up iSCSI and find where that DB is connected and then click the Connect button again. This will refresh the connection. All alerts should stop after that. Otherwise check for a failing or failed disk on your storage.

Hope it helps.

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